What does ISOLATED mean?

adjective

1. not close together in time“isolated instances of rebellion”
2. being or feeling set or kept apart from others“she felt detached from the group”
3. marked by separation of or from usually contiguous elements“little isolated worlds, as abruptly disjunct and unexpected as a palm-shaded well in the Sahara”
4. cut off or left behind“an isolated pawn”
5. under forced isolation especially for health reasons“a quarantined animal”
6. remote and separate physically or socially“existed over the centuries as a world apart”